hemophilia - Hemophilia is a recessive X-linked trait. Jill Smith is not a hemophiliac but is a carrier. She marries John Jones who is a hemophiliac. What is Jill's genotype?

Hemophilia is a recessive X-linked trait. Jill Smith is not a hemophiliac but is a carrier. She marries John Jones who is a hemophiliac. What is Jill's genotype?

10 viewed last edited 2 years ago

hemophilia genetic disorders

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Sangeetha Pulapaka (last edited 2 years ago) (Expert, Educator @Qalaxia)

A man who has hemophilia and a woman who is a carrier have:

A 25% (one in four) chance of having a son with hemophilia.
A 25% chance of having a son with normal blood clotting.
A 25% chance of having a daughter who is a carrier.
A 25% chance of having a daughter who has hemophilia.

Since women have two X chromosomes, they can have genotype X X - if the female is a carrier but is still normal.

XX (normal female)

X X- (carrier female)

However it is very rare for a man with hemophilia and a woman who is a carrier to get together. That is why there have been only few girls born with hemophilia.

Do have a look at this for more information:

https://www.hog.org/handbook/section/2/how-hemophilia-is-inherited

Qalaxia Knowlege Bot (last edited 2 years ago)

I found an answer from web.stanford.edu

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